منابع مشابه
Why should we still care about oncogenes?
Although oncogenes and their transformation mechanisms have been known for 30 years, we are just now using our understanding of protein function to abrogate the activity of these genes to block cancer growth. The advent of specific small-molecule inhibitors has been a tremendous step in the fight against cancer and their main targets are the cellular counterparts of viral oncogenes. The best-kn...
متن کاملWhy Should We Care About Molecular Coevolution?
Non-independent evolution of amino acid sites has become a noticeable limitation of most methods aimed at identifying selective constraints at functionally important amino acid sites or protein regions. The need for a generalised framework to account for non-independence of amino acid sites has fuelled the design and development of new mathematical models and computational tools centred on reso...
متن کاملWhy Should Theorists Care about Social Capital?
Social capital is embedded in social networks. For the purpose of these notes, I use the terms social capital and social networks interchangeably. At the most basic level it is useful to think of social capital in a supply-demand framework. Individual agents have some demand for social capital. More precisely, agents have demand for the services provided by social capital such as having access ...
متن کاملWhy doctors should care about animal cruelty.
BACKGROUND Animal cruelty is a significant problem for society, and there are good reasons why doctors should be particularly concerned by it. Increasing evidence for links between animal cruelty and child or spousal abuse is an area of growing concern internationally and of real importance to health professionals. OBJECTIVE This article aims to raise awareness of the relevance of animal crue...
متن کاملWhy should we care about fly tumors?
Drosophila is proving to be a valuable model for studying aggressive tumors induced by the combined activation of EGFR and JAK-STAT signaling. Here we summarize some of the most recent data showing that tissue damage and the modulation of common pathway regulators are at the heart tumor progression and metastasis.
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ژورنال
عنوان ژورنال: Science
سال: 2006
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.1136275